What players at 21 could impact this franchise right away?

[CJD]

Wynn, Hernandez and Nelson (won't be there) would start immediately at RG.
McClinchey would start immediately at RT.
Ragnow, Price and Daniels would start immediately at Center (something to be said about the state of our Oline that this is what we're saying about 3 of the 5 positions).
Payne and Vita would start immediately beside Atkins.
Hurst or Taven Bryan would spell Atkins and play on passing downs beside Atkins.
Derwin James would start immediately at either safety position.
Roquan Smith, Leighton Vander Esch or Tremaine Edwards would start immediately at nearly any LB position not occupied by Burfict.
Rashaan Evans or Arden Key would immediately play as a LB on passing downs as a pass rusher.
Hayden Hurst, Mike Gesicki and perhaps Dallas Goedert would play in 2 TE sets and spell Eifert until he gets injured, then they'd start.

That's 20 players. 1 of those players is guaranteed to be there :). And that's not even including the QBs, RBs and WRs that will inevitably be taken in the top 20 picks.